Tuesday, April 30, 2013

Initial Introduction To Hacking The Genome

Gentle Introduction

This Blog will offer a series of articles on how to develop Bioinformatics algorithms to sequence Genomic data in order to mine the knowledge lurking inside the genome sequences for us to gain more deeper insights on molecular function of the underlying disease.

Then , we will extend our knowledge to include the following set of topics :

  • NGS Data Analysis
  • Biological network analysis
  • How to Analyze Biological data in R (Statistical Programming language) 
  • Metabolomics (using Enzyme Kinetics and ordinary differential equations) to describe Any Metabolic network.

In our series of articles , we are going to introduce a new scripting language for writing algorithms that is new into this field , few scientists are using it which is called "Groovy" , Groovy is a new additions to JRE 7 (Java Runtime Environment) which is considered dynamic loosely typed scripting language on top of Java virtual machine , It combines the power of Any Scripting Language like Perl , Python...etc and the extremely flexible  programming framework of Java , that you can utilize any code written in java into groovy and vice versa , We will give gentle introduction to the building blocks of this script as we move on .

We will also utilize the latest technologies in analyzing genomic data like introducing Hadoop and Grid Computing in Computational Biology/Bioinformatics.

I hope you will enjoy these series as much as we will enjoy writing it .

Sincerely Yours;
Mohamed Ibrahim
Computational Biologist


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